Research and Reviews: Journal of Microbiology and Biotechnology

نویسندگان

  • Kamal Nayan Bajaj
  • Kamal Nayan
چکیده

Chloramphenicol has remained as a potent broad spectrum antibiotic over decades and due to its side effects its usage has been limited. In an era of increasing resistance to many antibacterial agents, chloramphenicol might have a role in the treatment of intra abdominal infections and respiratory tract infections caused by multi drug-resistant pathogens. This review article focuses on the spectrum of activity of chloramphenicol, mechanism of action , side effects , its parentral and oral use, its resistance mechanisms, toxicity elucidated by enteric pathogens against it and also on the possibility of its therapeutic use in treatment of multi drug resistant bacterial infections.

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تاریخ انتشار 2014